Over the years, we have developed a unique technique of packing
fused silica capillaries with sorbents in supercritical CO2
for SFC and HPLC separations. It allows to prepare highly efficient
columns with inner diameters of 50 – 500 µm, packed with particles
of 1 - 10 µm and up to several meters long.
Recently, we
have been focusing on the preparation of monolithic capillary
columns, made of silica gel or hybrid silica-organic materials
covering columns of 50 - 500 µm diameter. These columns offer
excellent performance, chemical stability, reproducibility and the
ability to easily change surface chemistry and selectivity of
separation. For special separations, we synthesize new stationary
phases and anchor them to the column surface.
