Instrumentation development

Novel concepts for miniaturized analytical systems are developed, including portable LC systems and LC-MS or CE-MS interfacing.

Collaborations

National Institute for NBC protection

separation and detection of hazardous compounds

INGOS, s. r. o.

transfer of our portable HPLC system to commerce

Projects

VB02000015 "Portable liquid chromatograph – Enhancing the technology readiness level, adaptation of advanced
optical detection and new applications" (2024-2026)

9F23002 "Development of High Sensitivity and High Resolution Analytical Tools for the Brain Glycans" (2023-2026)

Portable HPLC

Nanolitre-scale flow cells

Polyimide chip CE-MS interface

Glass chip CE-MS interface

Recent publications

Z. Gogaľová, V. Kahle, J. Šesták, An improved design of the fused silica capillary flow cell for absorbance detection in microcolumn liquid chromatography, Anal. Chim. Acta 1238 (2023) 340637.B. H. Lapizco-Encinas, Y. V. Zhang, P. P. Gqamana, J. Lavicka, F. Foret, Capillary electrophoresis as a sample preparation step to mass spectrometry analysis: A primer, Trends Anal. Chem. 164 (2023) 117093.J. Šesták, J. Planeta, V. Kahle, Compact optical detector utilizing light emitting diodes, 50 nL L-shaped silica capillary cell and CCD spectrometer for simultaneous multi-wavelength monitoring of absorbance and fluorescence in microcolumn liquid chromatography, Anal. Chim. Acta 1112 (2020) 80-91.J. Šesták, J. Planeta, V. Kahle, Nanolitre-scale cell based on L-shaped silica capillary and optical fibre for absorption photometric detection in capillary liquid chromatography, Anal. Chim. Acta 1073 (2019) 99-108.J. Krenkova, K. Kleparnik, J. Luksch, F. Foret, Microfabricated liquid junction hybrid capillary electrophoresis-mass spectrometry interface for fully automated operation, Electrophoresis 40 (2019) 2263-2270.