HOMERESEARCHPEOPLENEWSCONTACT
Department of Fluid Phase Separations
Department of
Fluid Phase Separations
Institute of Analytical Chemistry of the Czech Academy of SciencesInstitute of Analytical Chemistry of the CAS

Markers of isoelectric points

The research focuses on the development of low-molecular weight isoelectric point markers that are reasonable alternatives to the commonly used peptide and protein pI markers in isoelectric focusing.

There are 178 compounds with different absorption or fluorescence properties available upon request.

Recent publications

P. Dadajová, R. Čmelík, K. Šlais, F. Duša, Fluorescein-based low-molecular-mass markers of isoelectric point for tracing pH gradient using high sensitivity capillary isoelectric focusing with laser-induced fluorescence detection, Anal. Chim. Acta 1331 (2024) 343331.F. Duša, A. Kubesová, J. Šalplachta, D. Moravcová, Capillary isoelectric focusing - The role of markers of isoelectric point and recent applications in the field, Trends Anal. Chem. 162 (2023) 117018.F. Duša, D. Moravcová, K. Šlais, Low-molecular-mass colored compounds for fine tracing of pH gradient on broad and narrow scale in isoelectric focusing, Anal. Chim. Acta 1221 (2022) 340035.F. Duša, D. Moravcová, K. Šlais, Low-molecular-mass nitrophenol-based compounds suitable for the effective tracking of pH gradient in isoelectric focusing, Anal. Chim. Acta 1076 (2019) 144-153.